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Application of the Ibuprofen

None of us are not insured from pain – head, articulate, tooth, after operations and injuries … Sometimes pain develops at the most inappropriate moment, trying to overset our plans, disturbing work, the forthcoming scheduled meetings. Then Ibuprofen tablets can come to the rescue. They are appointed often to patients at complex treatment surgeons, traumatologists, nephrologists, therapists.
None of us are not insured from pain – head, articulate, tooth, after operations and injuries … Sometimes pain develops at the most inappropriate moment, trying to overset our plans, disturbing work, the forthcoming scheduled meetings, trips, sports performances. Then Ibuprofen tablets can come to the rescue. They are appointed often to patients at complex treatment surgeons, traumatologists, nephrologists, gynecologists, therapists, pediatricians. And sports doctors have it in the arsenal. Now there are many preparations under other trade names which active agent is the Ibuprofen. Therefore decided to tell in more detail about pharmacological effect of medicine, indications to application, contraindications and possible undesirable effects.
Применение Ибупрофена

The facts from history and the description of medicine

Применение Ибупрофена Many consider an ibuprofen as one of large and significant achievements of modern science – pharmacology. The history of a preparation began in the 1950th years. Then in Europe researches which purpose put search or creation of so-called "superaspirin" were approved. That is such preparation which would be similar on action to aspirin was required, but was transferred much better than the marked means. And scientists managed it therefore in 1969 in England for the first time began to use the Ibuprofen. And salycylates – the substances from plants possessing febrifugal and antipainful action which were successfully applied at the time of Hippocrates were the ancestor and the ancestor Ibuprofena.
The dosage form looks as round tablets of a biconvex form. The kernel at them white, and a surface becomes covered by a cover which color can be light pink or brightly pink. Active agent, that is the Ibuprofen, in one tablet of 200 mg. Excipients also are a part: edible gelatin, potato starch, wheat flour, vanillin, beeswax, magnesium stearate, colloidal dioxide of silicon, magnesium gidroksikarbonat, is seen low-molecular, the titan dioxide, sucrose, dye azorubin.
The ibuprofen is the representative of nonsteroid resolvents (in abbreviated form NPVS). This derivative fenilpropionovy acid.
Now this preparation had a large number of synonyms, that is medicines which active ingredient too is the Ibuprofen, simply let out these preparations different producers and the price at them significantly differs.
Here some of synonyms: Brufen, Nurofen, Snow-storm, Solpafleks, INSTANT 200 and INSTANT 400, Perofen, Faspik, Dolgit.

What action the preparation possesses?

The ibuprofen (the Latin name Ibuprofenum) renders analgeziruyushchy (that is soothing), anti-inflammatory and febrifugal action. The mechanism of action is connected with inhibition (blocking) of synthesis of prostaglandins – the substances responsible for feeling of pain, hyper thermal reactions and an inflammation. There are data that the preparation strengthens a producing endogenous interferon and renders the immunostimulating effect. One more fact – now experts research possibilities of application of a preparation for preventive actions and control of a cancer of a thick gut and Alzheimer's disease.

Indications to application

Применение Ибупрофена Here the list of diseases, situations and cases when application of the Ibuprofen for symptomatic therapy is recommended:
  • treatment of rheumatoid arthritises, polyarthritises, osteoarthrosis, gouty arthritis and other inflammations of joints, backbone;
  • the headache of various etiology (connected with tension, a depression, a stress);
  • menstrual pains;
  • migraines, mialgiya, neuralgia;
  • heat at colds and infections;
  • postoperative toothaches;
  • pains after injuries, including sports origin.

How to apply the Ibuprofen?

The dosage is selected and appointed by the doctor, considering character and the reasons of pain, and also age and a condition of the patient. At joint pains and inflammations to children after 12 years and the adult 3 or 4 times per day are appointed on 200 mg (one tablet). For strengthening of effect it is possible to accept and on 2 tablets, that is on 400 mg 3 times per day. Then the dose is reduced again. That the preparation was quicker soaked up and worked, the first dose accept to food in the morning. And in general it is desirable to take medicine after food that there were less by-effects. It is not necessary to take more than 6 pill per day. Without consultation of the doctor to accept a preparation not more long than 5 days.
If your child is less than 12 years old, the dose is selected by the doctor, considering also the weight of the little patient.

When the Ibuprofen is contraindicated?

Doctors do not appoint a preparation in the following cases:
  • existence at the patient of bronchial asthma;
  • aggravation of ulcer and erosive and inflammatory processes in a stomach, intestines;
  • hemophilia and hypocoagulation of blood;
  • bleedings in a stomach or intestines, intra cranial hemorrhages;
  • hemorrhagic diathesis;
  • liver failure and serious damages of kidneys, excess of potassium in an organism;
  • during the period after heart operation on aortocoronary shunting;
  • at hypersensitivity to compound components of medicine;
  • individual intolerance of NPVS which can be shown by rhinitis, the small tortoiseshell or even a bronchospasm;
  • pregnancy.
With care to apply during feeding by a breast. To children pediatricians appoint rectal candles, suspensions or syrups.

Side effects

Применение Ибупрофена It is considered that the preparation is transferred much better, than aspirin, diclofenac and indometacin. By-effects meet less often, but nevertheless I will mention them:
  • loss of appetite, heartburn, nausea, vomiting, diarrhea or lock, is very rare – ulcerations on mucous a stomach and the bleedings connected with it;
  • dryness or mouth pain, ulcerations of gums;
  • the itch and skin rashes, swelled Kvinke;
  • anaphylactic shock;
  • heat, sweating strengthening, allergic rhinitis, anemia;
  • short wind or bronchospasm;
  • sleeplessness, dizziness, headache, irritability and uneasiness;
  • noise (ring) in ears or decrease in hearing;
  • tachycardia, sometimes increase of a blood pressure, heart failure;
  • depression, drowsiness, confusion of consciousness, hallucination;
  • very seldom – doubling in eyes or not clear sight, dryness of eyes, puffiness of eyelids and a conjunctiva;
  • changes in composition of blood – agranulotsitoz, thrombocytopenia, a leykopeniye.
If there are listed above phenomena, it is necessary to refuse drug intake and to report about it to the doctor.

Whether the preparation interacts with other drugs?

It is not recommended to use during reception of the Ibuprofen also acetilsalicylic acid as in this case ability of acid to dilute blood will decrease and to interfere with a tromboobrazovaniye.
At simultaneous reception with anticoagulants and trombolitika there is a risk of bleedings.
The ibuprofen strengthens effect from insulin and other preparations reducing a glucose indicator in blood.
There are some more preparations which combined use with the Ibuprofen can lead to intoxication and strengthening of by-effects.

Whether overdose is possible?

Yes, if to use a preparation in the wrong doses, there can be following symptoms speaking about overdose: the nausea, vomiting which are followed by belly-ache, drowsiness, noise in ears, violations of a warm rhythm in hard cases – respiratory standstill and a coma.
In similar situations do to the patient washing of a stomach, give absorbent carbon and diuretics. If it is necessary, symptomatic therapy is appointed.

Special instructions

To avoid side effects, the preparation should be accepted in the correct dosage, short courses.
If long-term treatment is required nevertheless, it is carried out under control of a condition of blood, kidneys and the patient's liver.
In days of reception not to use ethanol (ethyl alcohol).
With care to use to persons which work demands speed of reaction and special attention.
The Ibuprofen in tablets on 200, 400 mg, in suppositories, ointments, creams, gels, syrups is issued.
To store in the home first-aid kit that it was inaccessible to children.
The ibuprofen is considered a preparation, highly effective and fast on action. It will easily relieve of pains of various origin. That the preparation brought benefit, it is necessary to get acquainted before reception with its possible by-effects and contraindications. recommends to the readers to consult to the doctor and the druggist by all means.
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